OUR PLATFORM

Melio's platform quickly & accurately identifies DNA/RNA sequences by combining novel DNA melting analysis & AI.  The platform assay and device is agnostic to the target sequence being profiled which allows us to uncover novel targets. 

Breakthrough Infectious Disease Diagnostics

Melio is developing clinically actionable, neat-patient pathogen identification platform for testing of all common infections. Our untargeted platform profiles each pathogen cell present in the sample in  tens of thousands of parallel reactions by capturing their unique sequence specific DNA melting profile. The platform allows us to identify known common bacterial, fungal and viral targets in the sample and also discover novel emerging threats. 

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FAST

Timely treatment

Comprehensive

 Single test, definitive diagnosis

Accessible

Affordable, Near-to-care

Accurate

Avoid shotgun treatments

Adaptable

Detect novel emerging threats

Selected Publications

Massively parallel digital high resolution melt for rapid and absolutely quantitative sequence profi

Massively parallel digital high resolution melt for rapid and absolutely quantitative sequence profi

Velez, Daniel Ortiz, et al. Scientific reports 7.1 (2017): 1-14.

Emerging technologies for molecular diagnosis of sepsis.

Emerging technologies for molecular diagnosis of sepsis.

Sinha, Mridu, et al. Clinical microbiology reviews 31.2 (2018): e00089-17.

A high-resolution digital DNA melting platform for robust sequence profiling and enhanced genotype d

A high-resolution digital DNA melting platform for robust sequence profiling and enhanced genotype d

Sinha, Mridu, et al. SLAS TECHNOLOGY: Translating Life Sciences Innovation 23.6 (2018): 580-591.

Improving quantitative power in digital PCR through digital high-resolution m

Improving quantitative power in digital PCR through digital high-resolution m

Aralar, April, et al. Journal of clinical microbiology 58.6 (2020): e00325-20.

Data-driven noise modeling of digital DNA melting analysis enables prediction of sequence discrimina

Data-driven noise modeling of digital DNA melting analysis enables prediction of sequence discrimina

Langouche, Lennart, et al. Bioinformatics (2020).